Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11)

• Catalog number
  CSB-EP023986MO-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Mouse Tumor necrosis factor ligand superfamily member 11(Tnfsf11),partial expressed in E.coli
• Specifications
  Uniprot ID: O35235; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 70-316aa; Sequence information: Extracellular Domain; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 43.9 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Tumor   necrosis   factor   ligand   superfamily   member   Tnfsf11  
• Gene symbol
  TNFSF11
• Short name
  Mouse Tumor necrosis factor ligand superfamily member 11 (Tnfsf11)
• Technique
  Mouse, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Mouse Tumor necrosis factor ligand supergroup member 11 (tumor necrosis factor (ligand) superfamily, member 11)
• Alternative technique
  murine
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 11, CD254 and hRANKL2 and ODF and OPGL and OPTB2 and RANKL and sOdf and TRANCE, TNFSF11 and IDBG-28393 and ENSG00000120659 and 8600, tumor necrosis factor receptor superfamily binding, Extracellular, Tnfsf11 and IDBG-182101 and ENSMUSG00000022015 and 21943, TNFSF11 and IDBG-628731 and ENSBTAG00000008924 and 513836
• Tissue
  tumor

Gene info

• Identity
  HGNC:11926
• Gene
  TNFSF11
• Long gene name
  TNF superfamily member 11
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 11
• Synonyms
  • TRANCE
  • RANKL
  • OPGL
  • ODF
  • CD254
• GenBank acession
  • AF013171
• Locus
  13q14
• Discovery year
  1998-12-04
• Pubmed identfication
  • 9312132
  • 9367155
• Classification
  • Tumor necrosis factor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000016807

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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