MAb to CD41 gpIIb IIIa Antibody
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Catalog number
GEN311781
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Price
Please ask
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Size
200ug
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Also known as
CD41, Platelet gpIIb IIIa
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Other names
CD41 antigen; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
SZ.22
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Host organism
Mouse (Mus musculus). Hybridization of X63-Ag14 myeloma cells with spleen cells from BALB/c mice. Source: Ascites
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CD41, Platelet gpIIb IIIa The molecular weight of the recognized antigen is 135kDa. CD41 is the integrin alpha IIb chain, also called gpIIb, which is non-covalently associated with the integrin beta 3 chain, also called gpIIIa (CD61), forming the gpIIbIIIa complex. Reacts with the alpha chain of gpIIb independently of the presence of gpIIIa. It reacts specifically with normal platelets and megakaryocytes but studeis have shown that it does not react with Glanzamann's thrombasthenic platelets which lack the membrane glycoprotein gpIIbIIIa. Does not inhibit the platelet aggregation and secretion induced by collagen, arachidonic acid and thrombin. Does not inhibit the fibrinogen binding to human platelets induced by ADP, arachidonic acid and PAF.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein A chromatography.
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Form Appearance
Purified, Lyophilized Reconstitute with 1ml distilled water.
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Concentration
0.2mg/ml (prior to lyophilization)
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Storage and shipping
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the reconstituted form for up to 1 month at 2 to 8 degree C.
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Tested applications
Flow Cytometry, Western Blot
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ITGA2B
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Short name
MAb CD41 gpIIb IIIa Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Alternative name
Anti-MAb to CD41 gpIIb IIIa
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
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Tree numbers
- E01.370.225.500.195.107.595.500.150
- E01.370.225.625.107.595.500.150
- E05.200.500.195.107.595.500.150
- E05.200.625.107.595.500.150
- E05.242.195.107.595.500.150
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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