(R)-Perharidine-1

  • Catalog number
    2615-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (R)-2-((3-Isopropyl)-7-(4-pyridin-2-yl)benzylamino)-3H-imidazo[4,5-b]pyridine-5-yl)amino)butan-1-ol
  • Description
    (R)-Perharidine-1 is a potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer . Also acts as a casein kinase 1 (CK1δ/ε) inhibitor. Inhibits the proliferation of various cancer cell lines.
  • CAS Number
    1133437-80-5
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₃₀N₆O
  • Molecular Weight
    430.55
  • Cell Permeable
    Yes
  • Purity
    >95% by NMR
  • Solubilities
    DMSO or EtOH
  • Handling
    Protect from air and light
  • Tag Line
    A potent CDK inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • SMILES
    CC[C@H](CO)NC1=CC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4C(N(C(C)C)C=N4)=N1
  • InChi
    InChI=1S/C25H30N6O/c1-4-20(15-32)29-23-13-22(24-25(30-23)31(16-28-24)17(2)3)27-14-18-8-10-19(11-9-18)21-7-5-6-12-26-21/h5-13,16-17,20,32H,4,14-15H2,1-3H3,(H2,27,29,30)/t20-/m1/s1
  • InChi Key
    VGHHVXRBOQENRA-HXUWFJFHSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    (R)-Perharidine-1
  • Alternative name
    (R)-Perharidine-1
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