Fostamatinib Disodium

• Catalog number
  1936-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (6-((5-Fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl dihydrogen phosphate, disodium
• Description
  A potent, ATP-competitive and selective Syk (Spleen tyrosine kinase) inhibitor (IC₅₀ = 41 nM). Inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling.
• CAS Number
  1025687-58-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₄FN₆O₉PNa₂
• Molecular Weight
  624.42
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, ATP-competitive and selective Syk inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD16628163
• PubChem CID
  25008120
• PubChem CID Link
• SMILES
  CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP (=O)([O-])[O-])C.[Na+].[Na+]
• InChi
  InChI=1S/C23H26FN6O9P.2Na/c1-23(2)21(31)30(11-38-40(32, 33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35- 3)18(37-5)16(9-12)36-4;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28, 29);;/q;2*+1/p-2
• InChi Key
  HSYBQXDGYCYSGA-UHFFFAOYSA-L
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fostamatinib   Disodium  
• Short name
  Fostamatinib Disodium
• Alternative name
  Fostamatinib Disodium

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