[5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)phenyl]-methanol
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Catalog number
F596745
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Price
Please ask
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Size
5 mg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
Please Inquire
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Cas number
This product doesn't have CAS Number
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Chemical s molecular weight
628.66
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Chemical s main applications
[5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)phenyl]-methanol is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
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Chemical s formula
C32H33FO10S
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Physical properties
White Solid
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
Chloroform, Ethyl Acetate, Methanol
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Stability conditions
No Data Available
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Storage
Refrigerator
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Description
N terminal acetylation or CH3CO as epigenetic regulation of [5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2 3 4 6-tetra-O- -β-D-glucopyranosyl)phenyl]-methanol by NATs. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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Gene target
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Short name
[5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2 3 4 6-tetra-O- -β-D-glucopyranosyl)phenyl]-methanol
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Alternative name
[5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)phenyl]-methanol
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