[5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)phenyl]-methanol

  • Catalog number
    F596745
  • Price
    Please ask
  • Size
    5 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
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  • Cas number
    This product doesn't have CAS Number
  • Chemical s molecular weight
    628.66
  • Chemical s main applications
    [5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)phenyl]-methanol is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
  • Chemical s formula
    C32H33FO10S
  • Physical properties
    White Solid
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    Chloroform, Ethyl Acetate, Methanol
  • Stability conditions
    No Data Available
  • Storage
    Refrigerator
  • Description
    N terminal acetylation or CH3CO as epigenetic regulation of [5-(4-Fluorophenyl)-2-thienyl][2-methyl-5-(2 3 4 6-tetra-O- -β-D-glucopyranosyl)phenyl]-methanol by NATs. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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