Recombinant Protease Activated Receptor 4 (PAR4)

Source

Prokaryotic expression
Predicted Molecular Mass KD

66.3kDa
Accurate Molecular Mass KD

66kDa
Organism species

Homo sapiens (Human)
Item Name

Protease Activated Receptor 4
Alternative Names

F2RL3; PAR-4; Coagulation Factor II Thrombin Receptor-Like 3; Coagulation factor II receptor-like 3
Research Area

Hematology;
Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits

Freeze-dried powder
Isoelectric Point

8.6
Purity

≥ 98%
Protein length

Gly48~Gln385
Tag

two N-terminal Tags, His-tag and GST-tag
Expression System

Prokaryotic expression
Application

Positive Control; Immunogen; SDS-PAGE; WB.
Manual link
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

Protease Activated Receptor PAR4
Gene symbol

F2RL3, PWAR4, PAWR
Short name

Recombinant Protease Activated Receptor 4 (PAR4)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E.coli
Species

Homo sapiens (Human)
Alternative name

Rec. Protease Activated Receptor 4 (PAR4)
Alternative technique

rec

Identity

HGNC:3540
Gene

F2RL3
Long gene name

F2R like thrombin or trypsin receptor 3
Synonyms gene name
- coagulation factor II (thrombin) receptor-like 3
- F2R like thrombin/trypsin receptor 3
Synonyms
- PAR4
Synonyms name
- proteinase-activated receptor-4
GenBank acession
- AF055917
Locus

19p13.11
Discovery year

1999-01-13
Entrez gene record

9002
Pubmed identfication
- 9618465
RefSeq identity
- NM_003950
Classification
- F2R receptors
VEGA ID

OTTHUMG00000182647
Locus Specific Databases
- LRG_633

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data