M-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-3074R-A488
  • Price
    Please ask
  • Size
    100ul
  • Long name
    M-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-M-CSF Receptor Tyr546 PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    M-CSF Receptor Tyr546
  • Specificity
    This is a highly specific antibody against M-CSF Receptor Tyr546.
  • Modification
    Phosphorylation
  • Modification Site
    Tyr546
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 546
  • Gene ID Number
    1436
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    C FMS; CD 115; CD115; CD115 antigen; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CSF1 R; CSF1R; CSFR; FIM 2; FIM2; CSF1R_HUMAN
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-M-CSF Receptor Tyr546 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • French translation
    anticorps
  • Gene target
    M-CSF   Receptor   Tyr546  
  • Gene symbol
    CSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
  • Short name
    Anti-M-CSF Receptor Tyr546
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 488
  • Alternative name
    M-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 488
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    interleukin 1 receptor associated kinase 3
  • Synonyms gene name
    • interleukin-1 receptor-associated kinase 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2002-07-17
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    phosphoglycerate mutase 2
  • Synonyms gene name
    • phosphoglycerate mutase 2 (muscle)
  • Synonyms
  • Locus
  • Discovery year
    1989-06-30
  • Entrez gene record
  • Classification
    • Phosphoglycerate mutases
    • Bisphosphoglycerate phosphatases
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    cytochrome P450 family 20 subfamily A member 1
  • Synonyms gene name
    • cytochrome P450, family 20, subfamily A, polypeptide 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2003-03-20
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Cytochrome P450 family 20
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    ubiquitin specific peptidase 16
  • Synonyms gene name
    • ubiquitin specific protease 16
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1999-07-09
  • Pubmed identfication
  • Classification
    • Ubiquitin specific peptidases
  • VEGA ID
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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