10058-F4
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Catalog number2739-25
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PricePlease ask
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Size25 mg
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Alternative_name5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
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Description10058-F4 is a c-Myc inhibitor that inhibits the c-Myc-Max associationn and function. It prevents the growth of fibroblasts in a c-Myc-dependent manner. Downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Induces cell cycle arrest, apoptosis and myeloid differentiation in human acute myeloid leukemia. 10058-F4 inhibits the MYCN/Max interaction leading to cell cycle arrest, apoptosis and neuronal differentiation in MYCN-amplified neuroblastoma cells.
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CAS Number403811-55-2
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Structure AvailableY
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Salt FormNo
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Molecular FormulaC₁₂H₁₁NOS₂
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Molecular Weight249.35
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Cell PermeableYes
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Purity≥98% by TLC
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SolubilitiesDMSO (60 mg/ml) or EtOH (20 mg/ml)
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HandlingProtect from air and light
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Tag LineA c-Myc inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00758517
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PubChem CID1271002
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SMILESCCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2
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InChiInChI=1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+
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InChi KeySVXDHPADAXBMFB-JXMROGBWSA-N
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MSDS AvailableYes
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Gene target
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Short name10058-F4
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Alternative name10058-F4
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