Rabbit Anti Human DISC1 Antibody-Non-conjugated

• Catalog number
  CSB-PA889093LA01HU_50ug
• Price
  Please ask
• Size
  50ug

• Long name
  Rabbit Antibody against Human DISC1, Non-conjugated
• Synonym name
  DISC1 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,WB,IF;Recommended dilution:WB:1:2000-1:10000,IF:1:50-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q9NRI5
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Disrupted in schizophrenia 1 protein (99-325AA)
• Immunogen species
  Human
• Alias
  Disrupted in schizophrenia 1 protein,DISC1,KIAA0457
• Background
  Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.
• Clonality
  Polyclonal antibody
• Shipping and storage
  DISC1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Disrupted in schizophrenia 1 protein
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  DISC1   Non-conjugated  
• Gene symbol
  DISC1, TSNAX-DISC1, DISC1-IT1, DISC2
• Short name
  Anti-DISC1
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  DISC1 Antibody
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:2888
• Gene
  DISC1
• Long gene name
  DISC1 scaffold protein
• Synonyms gene name
  • disrupted in schizophrenia 1
• GenBank acession
  • AF222980
• Locus
  1q42.2
• Discovery year
  2000-01-20
• Entrez gene record
  27185
• Pubmed identfication
  • 10814723
• RefSeq identity
  • NM_018662
• VEGA ID
  OTTHUMG00000037835

Gene info

• Identity
  HGNC:49177
• Gene
  TSNAX-DISC1
• Long gene name
  TSNAX-DISC1 readthrough (NMD candidate)
• Locus
  1q42.2
• Discovery year
  2013-09-24
• Entrez gene record
  100303453
• VEGA ID
  OTTHUMG00000183905

Gene info

• Identity
  HGNC:41325
• Gene
  DISC1-IT1
• Long gene name
  DISC1 intronic transcript 1
• Synonyms gene name
  • DISC1 intronic transcript 1 (non-protein coding)
• Locus
  1q42.2
• Discovery year
  2011-05-20
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000037834

Gene info

• Identity
  HGNC:2889
• Gene
  DISC2
• Long gene name
  disrupted in schizophrenia 2
• Synonyms gene name
  • disrupted in schizophrenia 2 (non-protein coding)
• Synonyms
  • DISC1-AS1
  • DISC1OS
  • NCRNA00015
• Synonyms name
  • DISC1 antisense RNA 1
  • non-protein coding RNA 15
• GenBank acession
  • AF222981
• Locus
  1q42.1
• Discovery year
  2000-01-20
• Entrez gene record
  27184
• Pubmed identfication
  • 10814723
  • 15478311
• RefSeq identity
  • NR_002227
• Classification
  • Long non-coding RNAs with non-systematic symbols

MeSH Data

• Name
  Micropore Filters
• Concept
  Scope note: A membrane or barrier with micrometer sized pores used for separation purification processes.
• Tree numbers
  • E05.196.454.403
  • E07.560
• Qualifiers
  parasitology, microbiology, ethics, virology, trends, veterinary, history, classification, economics, standards, supply & distribution, adverse effects, statistics & numerical data

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