Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against JWA.
1ug per 1ul
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JWA
Gene ID Number
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
JWA is a four-transmembrane environmental responsive protein which binds to the CC chemokine recepor 5 (CCR5), a major co-receptor for human immunodeficiency virus (HIV). JWA is involved in environmental stress-responsive pathways in K562 cells, an erythroleukemia cell line derived from patients with chronic myeloid leukemia. Environmental stressors to K562 cells such as heat shock, a higher temperature than the ideal body temperature of the organism from which the cell line was derived, and oxidative stress, the production of oxygen-centered free radicals, regulate and increase the expres-sion of JWA. This response to environmental stressors suggests similiarity of JWA to heat shock protein 70 (HSP70), which is upregulated by heat stress and toxic chemicals.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Addicsin; ADP ribosylation like factor 6 interacting protein 5; Aip 5; Aip5; ARL 6 interacting protein 5; ARL6IP5 antibody Cytoskeleton related vitamin A responsive protein; Dermal papilla derived protein 11; DERP 11; DERP11; Glutamate transporter EEAC 1 associated protein; Glutamate transporter EEAC1 associated protein; GTRAP3 18; Hp 22; Hp22; HSPC 127; HSPC127; JM 5; JM5; JMX; PRA 1 domain family 3; PRA 2; PRA1 domain family 3; PRA2; PRAF 3; PRAF3; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK activating protein PM27; PRAF3_HUMAN.