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EPZ 5676 for cell activation

EPZ 5676 for cell activation is available 2 times from Biovision labs

2382-1 | EPZ-5676 for cell activation size: 1 mg | 221.75 USD


2382-5 | EPZ-5676 for cell activation size: 5 mg | 701.01 USD

Catalog number 2382-5
Supplier Biovision
Price 701.01 USD
Size 5 mg
Product images
Description A potent and selective inhibitor of DOT1L methyltransferase (Ki = 80 pM). EPZ-5676 displays 37,000-fold selectivity over all other tested methyltransferases. It inhibits H3K79 methylation and MLL-fusion target gene expression and displays potent cell killing selective for acute leukemia lines bearing MLL translocations.
Peptide sequence N/A
CAS number 1380288-87-8
Molecular weight 562.71
Category Biochemicals
Other name (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol  
Molecular formula C₃₀H₄₂N₈O₃
Physical appearance Crystalline solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (~ 25 mg/ml)
Storage condition -20 ̊C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from light and air
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetEPZ-5676 for activation
Short name EPZ-5676 for activation
Technique activation
Alternative name EPZ-5676 to measure cellular activation
Tissue cell
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EPZ-5676 for activation | Technique alternative | 0101219871
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • EPZ-5676
  • for
  • activation
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