Epidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor precursor, ERBB, ERBB1, HER1, mENA, PIG61, Rece Antibody
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Catalog numberGEN632610
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PricePlease ask
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Size100ul
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Also known asEpidermal Growth Factor Receptor Receptor
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Other namesepidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameEGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Gene name synonimsEGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Other gene namesEGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone3i13
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens), Monkey, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes overexpressed levels of human EGF receptor only when phosphorylated at Tyr1068. Does not recognize other sites of tyrosine phosphorylation on EGF receptor, nor does it crossreact with other tyrosine-phosphorylated proteins. Species crossreactivity: rat and monkey.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAscites Ascites
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Form AppearanceSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsWestern Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolEGFR, EGFR-AS1, EGILA, RHBDF1
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Short nameEpidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor , ERBB, ERBB1, HER1, mENA, PIG61, Rece Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-Epidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor precursor, ERBB, ERBB1, HER1, mENA, PIG61, Rece
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Alternative techniqueantibodies
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Alternative to gene targetepidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Virusleukemia
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Gene info
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Identity
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Gene
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Long gene nameepidermal growth factor receptor
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Synonyms gene
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Synonyms gene name
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Erb-b2 receptor tyrosine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameEGFR antisense RNA 1
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Locus
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Discovery year2012-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameEGFR interacting lncRNA
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Synonyms
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Locus
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Discovery year2019-09-27
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
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Identity
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Gene
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Long gene namerhomboid 5 homolog 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Rhomboid family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
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Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery