TNF alpha protein
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Catalog number30R-2188
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PricePlease ask
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Size50 µg
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CategoryProteins
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Antibody SubtypeRecombinant Proteins
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Area of researchCytokines & Growth Factors
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SpecificityHuman
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ReactivityHuman
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Type of proteinRecombinant
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Expression SystemEscherichia coli
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Grade PurityGrater than 98% pure
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Method of PurificationTNF alpha protein was purified by affinity chromatography.
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Concentration500 ug/ml
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Form BufferProvided as a sterile liquid with 10 mM sodium phosphate, pH 7.2, 150 mM NaCl, and 1.0% BSA. 0.22 um filtered.
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StorageStore at -70 deg C or less.
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Shipping conditionsBlue Ice
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Tested forWB
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Usage RecommendationsWB: 1‐5 ug / ml
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BioactivityThe ED50 of this protein, as measured by L929 cytotoxicity assay, is less than or equal to 80 pg/ml. This corresponds to a specific activity of greater than or equal to1.3 x 10e7 Units/mg.
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Assay InformationIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
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DescriptionThe TNF alpha protein is a α- or alpha protein sometimes glycoprotein present in blood.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNF, TNFRSF1A, TNFRSF1B, LTBR
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Short nameTNF alpha protein
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Alternative namePurified recombinant Human TNF alpha protein
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Alternative to gene targettumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID