NKp46, Natural Cytotoxicity Receptor, Recombinant, Human (NCR NKp46, Natural Killer Cell Activating Receptor NKp46)

• Catalog number
  MBS637785
• Price
  Please ask
• Size
  0.005 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [NKp46, Natural Cytotoxicity Receptor]
• Other_names
  [natural cytotoxicity triggering receptor 1 isoform a; Natural cytotoxicity triggering receptor 1; natural cytotoxicity triggering receptor 1; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein]
• Other_gene_names
  [NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46]
• Purity
  Highly Purified95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
• Form
  Supplied as a liquid in PBS, pH 7.4 and 1mM EDTA.
• Storage_stability
  -20 degree CStability: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NKp46   Natural   Cytotoxicity   Receptor   NCR   NKp46   Natural   Killer   Activating   Receptor   NKp46  
• Gene symbol
  NCRUPAR
• Short name
  NKp46, Natural Cytotoxicity Receptor, Recombinant, (NCR NKp46, Natural Killer Activating Receptor NKp46)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  NKp46, Natural Cytotoxicity Receptor, Rec., H. sapiens (NCR NKp46, Natural Killer cellular Activating Receptor NKp46)
• Alternative technique
  rec
• Tissue
  cell

Gene info

• Identity
  HGNC:37153
• Gene
  NCRUPAR
• Long gene name
  non-protein coding RNA, upstream of F2R/PAR1
• Synonyms
  • ncR-uPAR
  • NCRNA00193
• Synonyms name
  • noncoding RNA upstream of the PAR-1
  • non-protein coding RNA 193
• Locus
  5q13.3
• Discovery year
  2009-07-29
• Entrez gene record
  100302746
• Pubmed identfication
  • 12084570
• RefSeq identity
  • NR_028375
• Classification
  • Long non-coding RNAs with non-systematic symbols

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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