NEDD8-AMC

• Catalog number
  4843-25
• Price
  Please ask
• Size
  25 ug

• Synonyms
  NEDD8-Aminomethylcoumarin
• Alternative_names
  NEDD8-Aminomethylcoumarin
• Description
  A protein implicated in cell cycle progression and cytoskeletal regulation
• Recombinant
  Yes
• Purity
  ≥95%
• Molecular Weight
  8.735 kDa
• Storage Temp
  -80°C
• Shipping
  Dry ice
• Shelf Life
  12 months
• Concentration
  1 mg/ml (DMSO)
• Appearance
  Liquid
• Physical form description
  A solution in DMSO ( 1 mg/ml)
• Background Information
  Prepared by the C-terminal derivatisation of NEDD8 with 7-amino-4-methylcoumarin. NEDD8-AMC acts as a useful and sensitive fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3. It is a useful reagent for the study of deNEDDylating activity where detection sensitivity or continuous monitoring of activity is essential.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet

• Gene target
  NEDD8-AMC  
• Gene symbol
  NEDD8-MDP1, NEDD8
• Short name
  NEDD8-AMC
• Alternative name
  NEDD8-AMC

Gene info

• Identity
  HGNC:39551
• Gene
  NEDD8-MDP1
• Long gene name
  NEDD8-MDP1 readthrough
• Locus
  14q12
• Discovery year
  2011-02-21
• Entrez gene record
  100528064
• RefSeq identity
  • NM_001199823.1
• VEGA ID
  OTTHUMG00000167107

Gene info

• Identity
  HGNC:7732
• Gene
  NEDD8
• Long gene name
  NEDD8 ubiquitin like modifier
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 8
• Synonyms
  • Nedd-8
• GenBank acession
  • D23662
• Locus
  14q12
• Discovery year
  1994-01-21
• Entrez gene record
  4738
• Pubmed identfication
  • 9353319
• RefSeq identity
  • NM_006156
• VEGA ID
  OTTHUMG00000029325

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