Recombinant Mouse Suppressor of cytokine signaling 1 (Socs1)

• Catalog number
  RPC22035-50ug
• Price
  Please ask
• Size
  50ug

• Estimated Turnaround Time
  6-11 business days
• Gene Name
  Socs1
• Alternative Names
  JAK-binding protein
• Source
  E.coli
• Purity
  > 85% by SDS-PAGE
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  12 months in lyophilized form; 6 months in solution form.
• Restriction
  For research use only. Not for diagnostic procedures.
• Description
  Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Suppressor   cytokine   signaling   Socs1  
• Gene symbol
  SOCS1
• Short name
  Recombinant Mouse Suppressor of cytokine signaling 1 (Socs1)
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mus musculus (Mouse), Mouses
• Alternative name
  Rec. Mouse Suppressor on cytokine signaling 1 (suppressor on cytokine signaling 1)
• Alternative technique
  rec, murine
• Alternative to gene target
  suppressor of cytokine signaling 1, CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, protein kinase binding, nuclei, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795

Gene info

• Identity
  HGNC:19383
• Gene
  SOCS1
• Long gene name
  suppressor of cytokine signaling 1
• Synonyms
  • SOCS-1
  • SSI-1
  • JAB
  • TIP3
  • Cish1
• GenBank acession
  • U88326
• Locus
  16p13.13
• Discovery year
  2002-11-13
• Pubmed identfication
  • 7796808
  • 9266833
• Classification
  • Suppressors of cytokine signaling
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000129792

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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