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Also known as
TNF-alpha
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Other names
tumor necrosis factor; Tumor necrosis factor; N/A; N/A; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-aCleaved into the following 6 chains:Tumor necrosis factor, membrane form; Alternative name(s):; N-terminal fragment
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
TNF
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Gene name synonims
N/A
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Other gene names
N/A; TNF; N/A; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
SB766
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
The IgG fraction of the tissue culture supernatant was purified by Protein G affinity chromatography.
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Form Appearance
Lyophilized from sterile filtered solution at a concentration of 1mg/ml in PBS pH 7.4.
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Concentration
N/A
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Storage and shipping
The lyophilized antibody is stable for at least 1 year from date of receipt the antibody should be stored at -20 degrees Celsius.. Upon reconstitution, the antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or the antibody should be stored at -20 degrees Celsius. for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles.
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Tested applications
N/A
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Description
The Monoclonal mouse Anti- TNF-alpha Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Latin name
Mus musculus
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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French translation
anticorps
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Gene target
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Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
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Short name
Monoclonal mouse Anti- TNF-alpha Antibody
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Technique
anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses
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Host
mouse
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Species
Human, Humans, Mouses
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Alternative name
Anti-Monoclonal mouse anti human TNF-alpha
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Alternative technique
antibodies, murine
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Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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