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Flavopiridol for cell activation

Flavopiridol for cell activation is available 2 times from Biovision labs

2090-1 | Flavopiridol for cell activation size: 1 mg | 167.15 USD

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2090-5 | Flavopiridol for cell activation size: 5 mg | 474.35 USD

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Description Cell-permeable. Flavopiridol is a synthetic flavonoid compound used as an anticancer agent. It is a serine/threonine kinase inhibitor that broadly targets cyclin-dependent kinases (CDKs), including the cyclin 9/cyclin T complex (pTEF-b), preventing activation of RNA polymerase II. Flavopiridol initiates cell cycle arrest and p53-independent apoptosis through down-regulation of Mcl-1 and X-linked inactivator of apoptosis (XIAP).
Peptide sequence N/A
CAS number 146426-40-6
Molecular weight 401.84
Category Biochemicals
Other name 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4-chromenone; HMR 1275; L86-8275; NSC 649890
Molecular formula C₂₁H₂₀ClNO₅
Physical appearance Yellow solid
Supplied with N/A
Is this a salt? N/A
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (~15 mg/ml ) or Ethanol (~ 8 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 24 months
Storage instructions Protect from light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetFlavopiridol for activation
Short name Flavopiridol for activation
Technique activation
Alternative name Flavopiridol to measure cellular activation
Tissue cell
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