CD104 (Integrin Beta-4) Antibody

  • Catalog number
    GEN438251
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    CD104
  • Other names
    integrin beta-4 isoform 1; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150; CD_antigen: CD104
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    ITGB4
  • Gene name synonims
    N/A
  • Other gene names
    ITGB4; ITGB4; CD104; N/A
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2a, kappa
  • Clone
    UM-A9
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    N/A
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
  • Tested applications
    Biological Blockade, ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    CD104   Integrin   Beta-4  
  • Gene symbol
    ITGB4
  • Short name
    CD104 (Integrin Beta-4) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-CD104 (Integrin Beta-4)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    integrin subunit beta 4
  • Synonyms gene name
    • integrin, beta 4
  • Synonyms
  • Locus
  • Discovery year
    1991-08-06
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Integrin beta subunits
    • Fibronectin type III domain containing
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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