CD104 (Integrin Beta-4) Antibody
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Catalog number
GEN438251
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Price
Please ask
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Size
100ug
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Also known as
CD104
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Other names
integrin beta-4 isoform 1; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150; CD_antigen: CD104
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
ITGB4
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Gene name synonims
N/A
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Other gene names
ITGB4; ITGB4; CD104; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2a, kappa
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Clone
UM-A9
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
N/A
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Concentration
N/A
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Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applications
Biological Blockade, ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ITGB4
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Short name
CD104 (Integrin Beta-4) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Alternative name
Anti-CD104 (Integrin Beta-4)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
integrin subunit beta 4
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1991-08-06
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Entrez gene record
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Pubmed identfication
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Classification
- Integrin beta subunits
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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