anti-NCLN Antibody

• Catalog number
  6789
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  NCLN Antibody: Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-β superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer's disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.
• Gene names
  NCLN Antibody: NET59, Nicalin, Nicastrin-like protein
• Antibodie s label
  unlabelled serum
• Purity
  NCLN Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  NCLN antibody was made against an 18 amino acid synthetic peptide near the carboxy terminus of human NCLN.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  NCLN antibody can be used for detection of NCLN by Western blot at 0.5 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 2.5 ug/mL.
• Suspention pH azide
  NCLN Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  NCLN antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  51873031
• Ncbi nr
  NP_064555
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  56926
• GENE symbol
  NCLN
• Antigene name
  nicalin
• Source
  Homo sapiens
• Protein nr
  Q969V3
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NCLN  
• Gene symbol
  NCLN
• Short name
  anti-NCLN Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNCLN (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:26923
• Gene
  NCLN
• Long gene name
  nicalin
• Synonyms gene name
  • nicalin homolog (zebrafish)
• Synonyms
  • NICALIN
  • NET59
• Synonyms name
  • nicastrin-like protein
• GenBank acession
  • BC025926
• Locus
  19p13.3
• Discovery year
  2004-11-26
• Entrez gene record
  56926
• Pubmed identfication
  • 11230166
  • 17261586
• RefSeq identity
  • NM_020170
• Classification
  • M28 metallopeptidases
• VEGA ID
  OTTHUMG00000180687

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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