RIP3 Antibody

  • Catalog number
    3293-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    RIP3
  • Target Alternative Name
    RIP like protein kinase 3, RIPK3, RIPK3
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Mouse, rat
  • Immunogen Sequence
    Synthetic peptide corresponding to residues surrounding amino acid 476 of mouse RIP3
  • Accession
    NP_001157580
  • Gene Id
    56532
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
  • Purification
    Affinity purified
  • Application
    Western blot, Immunohistochemistry
  • Application And Usages
    Western blotting (0.5-4 µg/ml) and in Immunohistochemistry (10-20 µg/ml). Rat kidney tissue section can be used as a positive control. An approximately 57 kDa band should be detected.
  • Description
    Receptor interacting protein including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the c-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, and mediates TNF-R1 mediated apoptosis, and attenuates RIP and TNFR1 induced NFkB activation. Overexpression of RIP3 induces apoptosis and NFkB activation.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    RIP3  
  • Gene symbol
    RIPK3
  • Short name
    RIP3 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    RIP3 (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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