RIP3 Antibody
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Catalog number3293-100
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PricePlease ask
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Size100 µg
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Antibody TargetRIP3
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Target Alternative NameRIP like protein kinase 3, RIPK3, RIPK3
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Antibody TypePolyclonal
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Species ReactivitiesMouse, rat
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Immunogen SequenceSynthetic peptide corresponding to residues surrounding amino acid 476 of mouse RIP3
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AccessionNP_001157580
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Gene Id56532
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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FormulationIn phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
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PurificationAffinity purified
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ApplicationWestern blot, Immunohistochemistry
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Application And UsagesWestern blotting (0.5-4 µg/ml) and in Immunohistochemistry (10-20 µg/ml). Rat kidney tissue section can be used as a positive control. An approximately 57 kDa band should be detected.
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DescriptionReceptor interacting protein including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the c-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, and mediates TNF-R1 mediated apoptosis, and attenuates RIP and TNFR1 induced NFkB activation. Overexpression of RIP3 induces apoptosis and NFkB activation.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRIPK3
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Short nameRIP3 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameRIP3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namereceptor interacting serine/threonine kinase 3
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Synonyms gene name
- receptor-interacting serine-threonine kinase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data