Irinotecan Hydrochloride

  • Catalog number
    1752-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’bipiperidine]-1’-carboxylate, Hydrochloride
  • Description
    An anticancer agent. This is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
  • CAS Number
    100286-90-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₃H₃₈N₄O₆. HCl
  • Molecular Weight
    623.14
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (50 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A DNA topoisomerase I inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD01862255
  • PubChem CID
    74990
  • SMILES
    CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
  • InChi
    InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2, 1-2H3;1H/t33-;/m0./s1
  • InChi Key
    GURKHSYORGJETM-WAQYZQTGSA-N
  • MSDS Available
    Yes
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