ITPR3 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-6471R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  ITPR3 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-ITPR3 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ITPR3
• Specificity
  This is a highly specific antibody against ITPR3.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ITPR3
• Gene ID Number
  3710
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  IP3R-III; IP3 receptor isoform 3; 4 antibody 5-trisphosphate receptor; 5-trisphosphate receptor type 3; FLJ36205; Inositol 1; Inositol 1,4,5 trisphosphate receptor type 3; IP3 receptor; IP3R 3; IP3R; IP3R3; ITPR 3; ITPR3; ITPR3_HUMAN; Type 3 inositol 1; Type 3 inositol 1,4,5 trisphosphate receptor; Type 3 InsP3 receptor.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-ITPR3 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  ITPR3  
• Gene symbol
  ITPR3
• Short name
  Anti-ITPR3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  ITPR3 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  inositol 1,4,5-trisphosphate receptor, type 3, IP3R and IP3R3, ITPR3 and IDBG-82972 and ENSG00000096433 and 3710, inositol 1, nuclei, Itpr3 and IDBG-156294 and ENSMUSG00000042644 and 16440, ITPR3 and IDBG-629118 and ENSBTAG00000013245 and 281879

Gene info

• Identity
  HGNC:6182
• Gene
  ITPR3
• Long gene name
  inositol 1,4,5-trisphosphate receptor type 3
• Synonyms gene name
  • inositol 1,4,5-triphosphate receptor, type 3
  • inositol 1,4,5-trisphosphate receptor, type 3
• Synonyms
  • IP3R3
• GenBank acession
  • D26351
• Locus
  6p21.31
• Discovery year
  1991-06-05
• Entrez gene record
  3710
• Pubmed identfication
  • 8081734
  • 8288584
• RefSeq identity
  • NM_002224
• Classification
  • Inositol 1,4,5-triphosphate receptors
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000014532

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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