MOUSE Anti-AMPK ALPHA 1/2 Antibody

• Catalog number
  GEN219501
• Price
  Please ask
• Size
  100ug

• Also known as
  AMPK ALPHA 1/2
• Other names
  5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; ACACA kinase; AMPK alpha 1; HMGCR kinase; AMPK subunit alpha-1; tau-protein kinase PRKAA1; acetyl-CoA carboxylase kinase; AMP -activate kinase alpha 1 subunit; hydroxymethylglutaryl-CoA reductase kinase; AMP-activated protein kinase, catalytic, alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; protein kinase, AMP-activated, alpha 1 catalytic subunit; Acetyl-CoA carboxylase kinase (EC:2.7.11.27); ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase (EC:2.7.11.31); HMGCR kinase; Tau-protein kinase PRKAA1 (EC:2.7.11.26)
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  AMPK ALPHA 1/2
• Gene name synonims
  N/A
• Other gene names
  PRKAA1; PRKAA1; AMPK; AMPKa1; AMPK1; AMPK subunit alpha-1; ACACA kinase; HMGCR kinase
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  84.1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Drosophila; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  AMPK ALPHA 1/2 This item recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilised by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels. _x000D_AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Purified (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0mg/ml
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
• Tested applications
  Immunohistology - Frozen (IHC), ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
• Description
  The MOUSE Anti-AMPK ALPHA 1/2 Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  AMPK   ALPHA   1/2  
• Gene symbol
  PRKAA2, SRPRA, CBX5, AGPAT1, DRAP1, SCART1, TUBA3D, TLK2, CAMK1, CTNNAL1
• Short name
  MOUSE Anti-AMPK ALPHA 1/2 Antibody
• Technique
  Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Anti-MOUSE ANTI AMPK ALPHA 1/2
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:9377
• Gene
  PRKAA2
• Long gene name
  protein kinase AMP-activated catalytic subunit alpha 2
• Synonyms gene
  • PRKAA
• Synonyms gene name
  • protein kinase, AMP-activated, alpha 2 catalytic subunit
• Synonyms
  • AMPK
  • AMPKa2
• GenBank acession
  • BC069823
• Locus
  1p32.2
• Discovery year
  1995-12-12
• Entrez gene record
  5563
• Pubmed identfication
  • 7959015
• RefSeq identity
  • NM_006252
• VEGA ID
  OTTHUMG00000008282

Gene info

• Identity
  HGNC:11307
• Gene
  SRPRA
• Long gene name
  SRP receptor subunit alpha
• Synonyms gene
  • SRPR
• Synonyms gene name
  • signal recognition particle receptor (docking protein)
• Synonyms
  • SRP-alpha
  • Sralpha
  • SR-alpha
• GenBank acession
  • BC001162
• Locus
  11q24.2
• Discovery year
  2001-06-22
• Entrez gene record
  6734
• Pubmed identfication
  • 3340536
  • 1312991
• RefSeq identity
  • NM_003139
• VEGA ID
  OTTHUMG00000165826

Gene info

• Identity
  HGNC:1555
• Gene
  CBX5
• Long gene name
  chromobox 5
• Synonyms gene name
  • chromobox homolog 5 (Drosophila HP1 alpha)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila)
  • chromobox homolog 5
• Synonyms
  • HP1Hs-alpha
  • HP1
  • HP1-ALPHA
• Synonyms name
  • HP1 alpha homolog (Drosophila)
• GenBank acession
  • U26311
• Locus
  12q13.13
• Discovery year
  1999-10-12
• Entrez gene record
  23468
• Pubmed identfication
  • 8663349
• RefSeq identity
  • NM_012117
• Classification
  • Chromobox family
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169700

Gene info

• Identity
  HGNC:324
• Gene
  AGPAT1
• Long gene name
  1-acylglycerol-3-phosphate O-acyltransferase 1
• Synonyms gene name
  • 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
• Synonyms
  • LPAAT-alpha
• Synonyms name
  • lysophosphatidic acid acyltransferase, alpha
• GenBank acession
  • U56417
• Locus
  6p21.32
• Discovery year
  1999-12-07
• Entrez gene record
  10554
• Pubmed identfication
  • 9461603
  • 9291118
• RefSeq identity
  • NM_006411
• Classification
  • MicroRNA protein coding host genes
  • 1-acylglycerol-3-phosphate O-acyltransferases
• VEGA ID
  OTTHUMG00000031210

Gene info

• Identity
  HGNC:3019
• Gene
  DRAP1
• Long gene name
  DR1 associated protein 1
• Synonyms
  • NC2-alpha
• Synonyms name
  • negative cofactor 2 alpha
  • DR1-associated corepressor
• GenBank acession
  • U41843
• Locus
  11q13.1
• Discovery year
  1998-09-22
• Entrez gene record
  10589
• Pubmed identfication
  • 8608938
• RefSeq identity
  • NM_006442
• VEGA ID
  OTTHUMG00000166723

Gene info

• Identity
  HGNC:32411
• Gene
  SCART1
• Long gene name
  scavenger receptor family member expressed on T cells 1
• Synonyms gene name
  • scavenger receptor family member expressed on T-cells 1
• Synonyms
  • CD163c-alpha
• Locus
  10q26.3
• Discovery year
  2017-02-28
• Entrez gene record
  619207
• Pubmed identfication
  • 19297026
  • 22795646
• RefSeq identity
  • NM_001396050
• Classification
  • Scavenger receptor cysteine rich domain containing

Gene info

• Identity
  HGNC:24071
• Gene
  TUBA3D
• Long gene name
  tubulin alpha 3d
• Synonyms
  • H2-ALPHA
• Synonyms name
  • alpha-tubulin isotype H2-alpha
• GenBank acession
  • K03460
• Locus
  2q21.1
• Discovery year
  2007-02-12
• Entrez gene record
  113457
• Pubmed identfication
  • 3785200
• RefSeq identity
  • NM_080386
• Classification
  • Tubulins
• VEGA ID
  OTTHUMG00000153600

Gene info

• Identity
  HGNC:11842
• Gene
  TLK2
• Long gene name
  tousled like kinase 2
• Synonyms gene name
  • tousled-like kinase 2
• Synonyms
  • PKU-ALPHA
  • MGC44450
• GenBank acession
  • AB004884
• Locus
  17q23.2
• Discovery year
  2000-01-07
• Entrez gene record
  11011
• Pubmed identfication
  • 9427565
  • 10523312
• RefSeq identity
  • NM_006852
• VEGA ID
  OTTHUMG00000179176

Gene info

• Identity
  HGNC:1459
• Gene
  CAMK1
• Long gene name
  calcium/calmodulin dependent protein kinase I
• Synonyms
  • CaMKI
  • CaMKI-alpha
• GenBank acession
  • L41816
• Locus
  3p25.3
• Discovery year
  1998-10-16
• Entrez gene record
  8536
• Pubmed identfication
  • 7641687
• RefSeq identity
  • NM_003656
• Classification
  • Calmodulin dependent protein kinases
• VEGA ID
  OTTHUMG00000128419

Gene info

• Identity
  HGNC:2512
• Gene
  CTNNAL1
• Long gene name
  catenin alpha like 1
• Synonyms gene name
  • catenin (cadherin-associated protein), alpha-like 1
  • catenin alpha-like 1
• Synonyms
  • CLLP
  • alpha-CATU
• Synonyms name
  • alpha-catulin
  • alpha2-catulin
• GenBank acession
  • AF030233
• Locus
  9q31.3
• Discovery year
  1998-12-09
• Entrez gene record
  8727
• Pubmed identfication
  • 9806841
• RefSeq identity
  • NM_003798
• VEGA ID
  OTTHUMG00000020466

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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