NFkB, p65, phosphorylated (Ser254) (NF-kB, Nuclear Factor kappa B, RelA)

  • Catalog number
    MBS625330
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [NFkB, p65]
  • Products_name_syn
    [Anti -NFkB, p65, phosphorylated (Ser254) (NF-kB, Nuclear Factor kappa B, RelA)]
  • Other_names
    [NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c; NF-kappa-B inhibitor-interacting Ras-like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; I-kappa-B-interacting Ras-like protein 2]
  • Other_gene_names
    [NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    Detects endogenous levels of NFkB p65 only when phosphorylated at threonine 254.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography
  • Form
    Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    ELISA (EL/EIA), Immunohistochemistry (IHC)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
  • Gene
    NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
  • Gene target
    NFkB   p65   phosphorylated   Ser254   NF-kB   Factor   kappa   RelA  
  • Gene symbol
    NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC, NFATC2, NFIL3
  • Short name
    NFkB, p65, phosphorylated (Ser254) (NF-kB, Factor kappa B, RelA)
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    NFkB, p65, phosphorylated (Ser254) (NF-kB, Nuclear Factor kappa B, v-v-rel reticuloendotheliosis viral oncogene homolog (avian) reticuloendotheliosis viral oncogene homolog A (avian))
  • Alternative to gene target
    v-rel reticuloendotheliosis viral oncogene homolog A (avian), NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, ankyrin repeat binding, nuclei, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, BT.26220 and IDBG-644222 and ENSBTAG00000013895 and 508233
Gene info
Gene info
  • Identity
    HGNC:7780
  • Gene
    NFE2
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q13.13
  • Discovery year
    1993-11-03
  • Entrez gene record
    4778
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
    OTTHUMG00000169761
Gene info
Gene info
Gene info
  • Identity
    HGNC:6057
  • Gene
    INA
  • Long gene name
    internexin neuronal intermediate filament protein alpha
  • Synonyms gene
  • Synonyms gene name
    • internexin neuronal intermediate filament protein, alpha
  • Synonyms
  • GenBank acession
  • Locus
    10q24.33
  • Discovery year
    1999-03-24
  • Entrez gene record
    9118
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intermediate filaments Type IV
  • VEGA ID
    OTTHUMG00000018986
Gene info
Gene info
  • Identity
    HGNC:7775
  • Gene
    NFATC1
  • Long gene name
    nuclear factor of activated T cells 1
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
    • nuclear factor of activated T-cells 1
  • Synonyms
  • GenBank acession
  • Locus
    18q23
  • Discovery year
    1994-11-16
  • Entrez gene record
    4772
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nuclear factors of activated T-cells
    • IPT domain containing
  • VEGA ID
    OTTHUMG00000132897
Gene info
Gene info
  • Identity
    HGNC:7776
  • Gene
    NFATC2
  • Long gene name
    nuclear factor of activated T cells 2
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    • nuclear factor of activated T-cells 2
  • Synonyms
  • GenBank acession
  • Locus
    20q13.2
  • Discovery year
    1994-11-16
  • Entrez gene record
    4773
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • IPT domain containing
    • Nuclear factors of activated T-cells
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000032747
Gene info
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NFkB p65 phosphorylated Ser254) (NF kB Factor kappa B RelA)
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