IL3R, phosphorylated (Tyr593) (Cytokine Receptor Common beta, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CD131, CDw131 antigen, CSF2RB, IL3RB, IL5RB)
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Catalog numberMBS627789
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PricePlease ask
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Size0.2 mL
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Products_typeAntibody
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Products_short_name[IL3R]
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Products_name_syn[Anti -IL3R, phosphorylated (Tyr593) (Cytokine Receptor Common beta, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CD131, CDw131 antigen, CSF2RB, IL3RB, IL5RB)]
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Other_names[interleukin-3 receptor subunit alpha isoform 2; Interleukin-3 receptor subunit alpha; interleukin-3 receptor subunit alpha; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; interleukin 3 receptor, alpha (low affinity)]
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Other_gene_names[IL3RA; IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificityRecognizes human IL3R when phosphorylated at Tyr593.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormSupplied as a liquid in PBS, 0.09% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationELISA (EL/EIA), Immunohistochemistry (IHC)
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DescriptionAntigens are peptides or recombinant or native dependent on the production method. Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GeneGranulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
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Gene target
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Gene symbolCSF2RB, IL3, CSF2, IL5, IL36G, IL25, IL22, IL18, IL37, IL6R
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Short nameIL3R, phosphorylated (Tyr593) (Cytokine Receptor Common beta, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CD131, CDw131 antigen, CSF2RB, IL3RB, IL5RB)
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Techniqueantigen, antigenes
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HostRabbit
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IsotypeIgG
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Alternative nameIL3R, phosphorylated (Tyr593) (Cytokine Receptor Common b, GM-CSF/Interleukin-3/Interleukin-5 Receptor Common b functionnal sequence, CD131, CDw131 protein, colony stimulating factor 2 receptor, b, low-affinity (granulocyte-macrophage), IL3RB, IL5RB)
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Alternative techniqueantigenes
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Alternative to gene targetcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), CD131 and CDw131 and IL3RB and IL5RB and SMDP5, CSF2RB and IDBG-6178 and ENSG00000100368 and 1439, protein binding, Plasma membranes, CSF2RB and IDBG-638112 and ENSBTAG00000009064 and 528530
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Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2 receptor subunit beta
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Synonyms gene
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Synonyms gene name
- colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
- colony stimulating factor 2 receptor beta common subunit
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-08-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 3
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Synonyms gene name
- interleukin 3 (colony-stimulating factor, multiple)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2
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Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 5
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Synonyms gene name
- interleukin 5 (colony-stimulating factor, eosinophil)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 25
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Synonyms gene
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Synonyms gene name
- interleukin 17E
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Synonyms
-
GenBank acession
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Locus
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Discovery year2001-01-26
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Pubmed identfication
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinterleukin 18
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Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 37
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 7 (zeta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 6 receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data