CD1c Antibody

• Catalog number
  F42959-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CD1c
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the CD1c antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CD1c antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P29017
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
• Immunogen
  A portion of amino acids 226-253 from the human protein was used as the immunogen for this CD1c antibody.
• Storage
  Aliquot the CD1c antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD1c  
• Gene symbol
  CD1C
• Short name
  Anti-CD1c
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CD1c
• Alternative technique
  antibodies
• Alternative to gene target
  CD1c molecule, BDCA1 and CD1 and CD1A and R7, CD1C and IDBG-103739 and ENSG00000158481 and 911, lipopeptide binding, Plasma membranes

Gene info

• Identity
  HGNC:1636
• Gene
  CD1C
• Long gene name
  CD1c molecule
• Synonyms gene
  • CD1
• Synonyms gene name
  • CD1C antigen, c polypeptide
  • CD1c antigen
• GenBank acession
  • M28827
• Locus
  1q23.1
• Discovery year
  1988-05-11
• Entrez gene record
  911
• Pubmed identfication
  • 2447586
• RefSeq identity
  • NM_001765
• Classification
  • C1-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000017514

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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