8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3- methyl-1--[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione; BI-1356
An antidiabetic agent. Acts as a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down glucagon-like peptide 1 (GLP-1). Prevents the inactivation of endogenous GLP-1 and GIP through competitive inhibition of the DPP IV enzyme.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from light and moisture
Maximum time for storage
White to yellowish solid
DMSO (>15 mg/ml) or H₂O (
For cells, cell lines and tissues in culture till half confluency.