PLC gamma 1 (Tyr771) Antibody, ALEXA FLUOR 488
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Catalog number
bs-3460R-A488
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Price
Please ask
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Size
100ul
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Long name
PLC gamma 1 (Tyr771) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
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Also known as
Anti-PLC gamma 1 Tyr771 PAb ALEXA FLUOR 488
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 488
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
PLC gamma 1 Tyr771
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Specificity
This is a highly specific antibody against PLC gamma 1 Tyr771.
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Modification
Phosphorylation
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Modification Site
Tyr771
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr771
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Gene ID Number
5335
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
499nm/519nm
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Synonyms
PLC 1; PLC 148; PLC gamma 1; PLC II; PLC1; PLC148; PLCG 1; PLCG1; PLCgamma1; PLCII; triphosphoinositide phosphodiesterase; 1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; phosphodiesterase gamma 1; phosphoinositidase C; phosphoinositide phospholipase C; Phospholipase C 148; phospholipase C gamma 1 formerly subtype 148; Phospholipase C gamma 1; phospholipase C-148; PLCG1_HUMAN.
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-PLC gamma 1 Tyr771 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor
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French translation
anticorps
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Gene target
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Gene symbol
PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
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Short name
Anti-PLC gamma 1 Tyr771
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 488
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Alternative name
PLC gamma 1 (Tyr771) Polyclonal Antibody, ALEXA FLUOR 488
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
phospholipase C beta 1
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Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-21
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
phospholipase C gamma 1
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Synonyms gene
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Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
phospholipase C eta 2
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Synonyms gene
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Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2004-07-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- Phospholipases
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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