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Target antigen
NDRG1
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, mouse, rat
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Analyses
WB,IHC-P
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Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human NDRG1(194-214aa HLFGKEEMQSNVEVVHTYRQH).
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the NDRG1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The NDRG1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene. It is a member of the N-myc downregulated gene family which belong to the alpha/beta hydrolase superfamily. The NDRG1 gene is mapped to chromosome 8q24. It has got a deduced 394 amino acid protein with a molecular mass of 43kD. NDRG1 is expressed in the cytoplasm and basolateral membranes of gut lumen surface epithelial cells. The protein appears to play a vital role in growth arrest and cell differentiation.
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Related articles
1. van Belzen N, Dinjens WN, Diesveld MP, Groen NA, van der Made AC, Nozawa Y, Vlietstra R, Trapman J, Bosman FT (Sep 1997). "A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms". Lab Invest 77 (1): 85–92. PMID 9251681. 2. Kokame K, Kato H, Miyata T (Jan 1997). "Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes". J Biol Chem 271 (47): 29659–65. 3. Zhang J, Chen S, Zhang W, Zhang J, Liu X, Shi H, Che H, Wang W, Li F, Yao L (Jun 2008). "Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region". Gene 417 (1-2): 5–12. 4. "Entrez Gene: NDRG1 N-myc downstream regulated gene 1".
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Gene Name
NDRG1
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Protein Name
Protein NDRG1
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Gene Full Name
N-myc downstream regulated 1
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Synonyms
42 kDa antibody|Anti GC4 antibody|cap43 antibody|cmt4d antibody|Differentiation related gene1 protein antibody|Differentiation-related gene 1 protein antibody|Drg 1 antibody|DRG-1 antibody|drg1 antibody|gc4 antibody|GC4 antibody antibody|hmsnl antibody|Human mRNA for RTP complete cds antibody|N myc downstream regulated gene 1 antibody|N myc downstream regulated gene 1 protein antibody|N-myc downstream-regulated gene 1 protein antibody|Ndr 1 antibody|ndr1 antibody|NDRG 1 antibody|Ndrg1 antibody|NDRG1 protein antibody|NDRG1_HUMAN antibody|Nickel specific induction protein antibody|Nickel specific induction protein Cap43 antibody|Nickel-specific induction protein Cap43 antibody|nmsl antibody|Nmyc downstream regulated antibody|Nmyc downstream regulated gene1 antibody|Nmyc downstream regulated gene1 protein antibody|Protein NDRG1 antibody|Protein regulated by oxygen 1 antibody|Protein regulated by oxygen1 antibody|proxy1 antibody|Reduced in tumor antibody|reducin antibody|Reducing agents and tunicamycin responsive protein antibody|Reducing agents and tunicamycin-responsive protein antibody|rit42 antibody|rtp antibody|targ1 antibody|TDD5 antibody|tdds antibody|Tunicamycin responsive protein antibody|tunicamycin-responsive protein antibody
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Uniprot ID
Q92597
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
