CDK5 (8A1) Monoclonal Antibody

• Catalog number
  bsm-50178M
• Price
  Please ask
• Size
  0.1ml

• Long name
  CDK5 (8A1) Monoclonal Antibody
• Also known as
  CDK5 (8A1) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CDK5
• Specificity
  This is a highly specific antibody against CDK5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  8A1
• Source
  His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells.
• Gene ID number
  1020
• Swiss Prot
  Q00535
• Tested Applications
  WB, IP
• Recommended dilutions
  WB (1:1000 ~ 2000) IP (2 ul)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.
• Purification method
  Ammonium sulfate precipitation
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  LIS7; PSSALRE; Cyclin-dependent-like kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; CDK5; CDKN5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CDK5   8A1   Monoclonal  
• Gene symbol
  CDK5
• Short name
  Anti-CDK5
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)2b κ
• Alternative name
  CDK5 (8A1) Monoclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  cyclin-dependent kinase 5, PSSALRE, CDK5 and IDBG-48977 and ENSG00000164885 and 1020, transferase activity, nuclei, Cdk5 and IDBG-141112 and ENSMUSG00000028969 and 12568, CDK5 and IDBG-637527 and ENSBTAG00000007766 and 281066

Gene info

• Identity
  HGNC:1774
• Gene
  CDK5
• Long gene name
  cyclin dependent kinase 5
• Synonyms
  • PSSALRE
• GenBank acession
  • X66364
• Locus
  7q36.1
• Discovery year
  1993-07-28
• Entrez gene record
  1020
• Pubmed identfication
  • 8275715
  • 1639063
• Classification
  • Cyclin dependent kinases
• VEGA ID
  OTTHUMG00000158414

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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