Roundabout homolog 1 antibody ROBO1 - Blocking Peptide
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Catalog number
X2335B
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Price
Please ask
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Size
50 μg
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Category
Proteins & Peptides
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Long description
Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.
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Antibody come from
Synthetic peptide derived from human FLAP protein.
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Other description
Provided as solution in phosphate buffered saline.
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Clone
not specified
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Antigen antibody binding interaction
Roundabout homolog 1 antibody ROBO1 - Blocking Peptide
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Western Blot
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Antibody s suited for
For use with FLAP polyclonal antibodies (Cat. No. X2318P & X2350P).
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Storage
-20ºC
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Relevant references
1. Dixon, R.A.F., et al. 'Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.; Nature 343:282-284(1990)._x000B__x000B_2. Helgadottir, A., et al. 'The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.; Nat. Genet. 36:233-239(2004).
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Properties
If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. blocking peptide
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Test
You can block the antibody by the specific target amino acid sequence of peptide.
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Description
Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
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French translation
anticorps
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Gene target
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Gene symbol
ROBO1
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Short name
Roundabout homolog 1 antibody ROBO1 - Blocking Peptide
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Technique
blocking peptide, Antibody, Blocking, peptide, antibodies against human proteins, antibodies for, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
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Isotype
not specified
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Label
unlabeled
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Alternative name
Roundabout homolog 1 (antibody to-) roundabout, axon guidance receptor, homolog 1 (Drosophila) - inhibiting short protein sequence
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Alternative technique
control, antibodies, peptides
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Alternative to gene target
roundabout, axon guidance receptor, homolog 1 (Drosophila), DUTT1 and SAX3, ROBO1 and IDBG-45469 and ENSG00000169855 and 6091, protein heterodimerization activity, Cell surfaces, Robo1 and IDBG-171072 and ENSMUSG00000022883 and 19876, ROBO1 and IDBG-630648 and ENSBTAG00000009851 and 536815
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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