Filters
US: (408) 780-0908 | EU: 0032 16 58 90 45 lieven@gentaur.com
Total records: 2499605. Total pages:Pages 49993 First Current page: 1 Last

anti-EGFR Antibody

  • Catalog number
    3782-100
  • Product name
    anti-EGFR Antibody
  • Size
    EGFR Antibody
  • Price
    338EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide of human EGFR
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunoprecipitation
  • Target of this antibody:
    EGFR
  • Formulation of this antibody:
    100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
  • Alternative names of antibody target:
    EGFR, Epidermal Growth Factor Receptor, ERBB, ERBB1, ERBB-1, Erythroblastic Leukemia viral (v-erb-b) oncogene homolog
  • Recommended usage:
    Western blotting (1:500 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the EGFR of human and mouse origins. Reactivity to other species has not been tested.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. Exons in the EGFR gene product are frequently either deleted or duplicated to produce deletion mutants (DM) or tandem duplication mutants (TDM), respectively, which are detected at various molecular weights. EGFR binds several ligands, including epidermal growth factor (EGF), transforming growth factor α (TGFα), Amphiregulin and heparin binding-EGF (HB-EGF). Ligand binding promotes the internalization of EGFR via Clathrin-coated pits and its subsequent degradation in response to its intrinsic tyrosine kinase. EGFR is involved in organ morphogenesis and maintenance and repair of tissues, but upregulation of EGFR is associated with tumor progression. The oncogenic effects of EGFR include initiation of DNA synthesis, enhanced cell growth, invasion and metastasis. Abrogation of EGFR results in cell cycle arrest, apoptosis or dedifferentiation of cancer cells, suggesting that EGFR may be an effective therapeutic target.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-EGFR Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-epidermal growth factor receptor (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001503 and ossification and biological process this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001942 and hair follicle development and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005006 and epidermal growth factor-activated receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006412 and translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0006970 and response to osmotic stress and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007411 and axon guidance and biological process this GO :0007435 and salivary gland morphogenesis and biological process this GO :0007611 and learning or memory and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010960 and magnesium ion homeostasis and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016101 and diterpenoid metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016772 and transferase activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019694 and alkanesulfonate metabolic process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021795 and cerebral cortex cell migration and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030122 and AP-2 adaptor complex and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0030235 and nitric-oxide synthase regulator activity and molecular function this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031659 and positive regulation of cyclin-dependent protein kinase activity involved in G1/S and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0032355 and response to estradiol and biological process this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033590 and response to cobalamin and biological process this GO :0033594 and response to hydroxyisoflavone and biological process this GO :0033993 and response to lipid and biological process this GO :0035413 and positive regulation of catenin import into nucleus and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035690 and cellular response to drug and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042698 and ovulation cycle and biological process this GO :0042743 and hydrogen peroxide metabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043006 and activation of phospholipase A2 activity by calcium-mediated signaling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043586 and tongue development and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048143 and astrocyte activation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048408 and epidermal growth factor binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048546 and digestive tract morphogenesis and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051205 and protein insertion into membrane and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051968 and positive regulation of synaptic transmission, glutamatergic and biological process this GO :0060571 and morphogenesis of an epithelial fold and biological process this GO :0070141 and response to UV-A and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070435 and Shc-EGFR complex and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, transferase activity, this GO :0001948: glycoprotein binding and also this GO :0003682: chromatin binding and also this GO :0003690: double-stranded DNA binding and also this GO :0004672: protein kinase activity and also this GO :0004709: MAP kinase kinase kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004716: receptor signaling protein tyrosine kinase activity and also this GO :0004871: signal transducer activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005006: epidermal growth factor-activated receptor activity and also this GO :0005102: receptor binding and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, transferring phosphorus-containing groups and also this GO :0019899: enzyme binding and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0030235: nitric-oxide synthase regulator activity and also this GO :0042802: identical protein binding and also this GO :0046982: protein heterodimerization activity and also this GO :0048408: epidermal growth factor binding and also this GO :0051015: actin filament binding, this GO :0001948: glycoprotein binding, this GO :0003682: chromatin binding, this GO :0003690: double-stranded DNA binding, this GO :0004672: protein kinase activity, this GO :0004709: MAP kinase kinase kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004716: receptor signaling protein tyrosine kinase activity, this GO :0004871: signal transducer activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005006: epidermal growth factor-activated receptor activity, this GO :0005102: receptor binding, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016301: kinase activity, this GO :0016772: transferase activity, transferring phosphorus-containing groups, this GO :0019899: enzyme binding, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0030235: nitric-oxide synthase regulator activity, this GO :0042802: identical protein binding, this GO :0046982: protein heterodimerization activity, this GO :0048408: epidermal growth factor binding, this GO :0051015: actin filament binding, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
1. Gene info
Related products
Chat with gentaur.com employee