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anti-CTBP1 Antibody

  • Catalog number
    3796-100
  • Product name
    anti-CTBP1 Antibody
  • Size
    CTBP1 Antibody
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide of human CTBP1
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    CTBP1
  • Formulation of this antibody:
    100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
  • Alternative names of antibody target:
    CTBP, CTBP1, CTBP-1, C-Terminal Binding Protein 1
  • Recommended usage:
    Western blotting (1:500 – 1:2000). However, the optimal concentrations should be determined individually. HeLa nuclear extract (Cat.# 1641-1) can be used as a positive control. The antibody recognizes the CTBP1 of human and mouse origins. Reactivity to other species has not been tested.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T-cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of ∂EF1, a cellular zinc finger-homeodomain protein, and thereby enhances ∂EF1 induced transcriptional silencing. In addition, CtBP complexes with CtIP, a protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-CTBP1 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-C-terminal binding protein 1 (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    C-terminal binding protein 1, BARS, CTBP1 and IDBG-6522 and ENSG00000159692 and 1487, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001106 and RNA polymerase II transcription corepressor activity and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004616 and phosphogluconate dehydrogenase (decarboxylating) activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005829 and cytosol and cellular component this GO :0006098 and pentose-phosphate shunt and biological process this GO :0006351 and transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007030 and this GO lgi organization and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008152 and metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016616 and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and molecular function this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019079 and viral genome replication and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0031065 and positive regulation of histone deacetylation and biological process this GO :0034401 and regulation of transcription by chromatin organization and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0050872 and white fat cell differentiation and biological process this GO :0051287 and NAD binding and molecular function this GO :0051726 and regulation of cell cycle and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0090241 and negative regulation of histone H4 acetylation and biological process, oxidoreductase activity, this GO :0001106: RNA polymerase II transcription corepressor activity and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004616: phosphogluconate dehydrogenase (decarboxylating) activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0008134: transcription factor binding and also this GO :0016616: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and also this GO :0019904: protein domain specific binding and also this GO :0042803: protein homodimerization activity and also this GO :0051287: NAD binding and also this GO :0070491: repressing transcription factor binding, this GO :0001106: RNA polymerase II transcription corepressor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004616: phosphogluconate dehydrogenase (decarboxylating) activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0008134: transcription factor binding, this GO :0016616: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, this GO :0019904: protein domain specific binding, this GO :0042803: protein homodimerization activity, this GO :0051287: NAD binding, this GO :0070491: repressing transcription factor binding, nuclei, Ctbp1 and IDBG-152845 and ENSMUSG00000037373 and 13016, CTBP1 and IDBG-643874 and ENSBTAG00000008480 and 513131
1. Gene info
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