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anti-AGT Antibody (NT)

  • Catalog number
    6709-100
  • Product name
    anti-AGT Antibody (NT)
  • Size
    AGT Antibody (NT)
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human
  • Purification method:
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Immunogene sequence:
    This AGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT.
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, IHC
  • Target of this antibody:
    AGT
  • Formulation of this antibody:
    100 µl of antibody in PBS with 0.09% (W/V) sodium azide
  • Alternative names of antibody target:
    AGT; SERPINA8; Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin I; Angiotensin-2; Angiotensin II; Angiotensin-3; Angiotensin III;
  • Recommended usage:
    Western blot: ~1:1000, IHC: ~1:10-1:50
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    Angiotensinogen, also known as AGT and SERPINA8, is a member of the serpin family. It is anα-2-globulinthat is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. It is expressed by the liver and secreted in plasma. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system. Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD).
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-AGT Antibody (NT)
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (Antibody to) (NT)
  • Alternative technique
    antibodies
  • Alternative to gene target
    angiotensinogen (serpin peptidase inhibitor, clade A, member 8), ANHU and SERPINA8, AGT and IDBG-107363 and ENSG00000135744 and 183, this GO :0001543 and ovarian follicle rupture and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0001568 and blood vessel development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0001822 and kidney development and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0001991 and regulation of systemic arterial blood pressure by circulatory renin-angiotensin and biological process this GO :0001998 and angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure and biological process this GO :0001999 and renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure and biological process this GO :0002003 and angiotensin maturation and biological process this GO :0002016 and regulation of blood volume by renin-angiotensin and biological process this GO :0002018 and renin-angiotensin regulation of aldosterone production and biological process this GO :0002019 and regulation of renal output by angiotensin and biological process this GO :0002034 and regulation of blood vessel size by renin-angiotensin and biological process this GO :0002035 and brain renin-angiotensin system and biological process this GO :0003014 and renal system process and biological process this GO :0003051 and angiotensin-mediated drinking behavior and biological process this GO :0003331 and positive regulation of extracellular matrix constituent secretion and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007199 and G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007565 and female pregnancy and biological process this GO :0007568 and aging and biological process this GO :0007588 and excretion and biological process this GO :0008065 and establishment of blood-nerve barrier and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009409 and response to cold and biological process this GO :0009651 and response to salt stress and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010535 and positive regulation of activation of JAK2 kinase activity and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010873 and positive regulation of cholesterol esterification and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0014061 and regulation of norepinephrine secretion and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014824 and artery smooth muscle contraction and biological process this GO :0014873 and response to muscle activity involved in regulation of muscle adaptation and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0030162 and regulation of proteolysis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030432 and peristalsis and biological process this GO :0031701 and angiotensin receptor binding and molecular function this GO :0031702 and type 1 angiotensin receptor binding and molecular function this GO :0031703 and type 2 angiotensin receptor binding and molecular function this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033864 and positive regulation of NAD(P)H oxidase activity and biological process this GO :0034104 and negative regulation of tissue remodeling and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0035411 and catenin import into nucleus and biological process this GO :0035813 and regulation of renal sodium excretion and biological process this GO :0035815 and positive regulation of renal sodium excretion and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042310 and vasoconstriction and biological process this GO :0042311 and vasodilation and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042756 and drinking behavior and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045723 and positive regulation of fatty acid biosynthetic process and biological process this GO :0045742 and positive regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0045777 and positive regulation of blood pressure and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0046622 and positive regulation of organ growth and biological process this GO :0048143 and astrocyte activation and biological process this GO :0048144 and fibroblast proliferation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048659 and smooth muscle cell proliferation and biological process this GO :0050663 and cytokine secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051387 and negative regulation of neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051924 and regulation of calcium ion transport and biological process this GO :0051969 and regulation of transmission of nerve impulse and biological process this GO :0061049 and cell growth involved in cardiac muscle cell development and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070471 and uterine smooth muscle contraction and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, type 2 angiotensin receptor binding, this GO :0004867: serine-type endopeptidase inhibitor activity and also this GO :0005179: hormone activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0031701: angiotensin receptor binding and also this GO :0031702: type 1 angiotensin receptor binding and also this GO :0031703: type 2 angiotensin receptor binding, this GO :0004867: serine-type endopeptidase inhibitor activity, this GO :0005179: hormone activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0031701: angiotensin receptor binding, this GO :0031702: type 1 angiotensin receptor binding, this GO :0031703: type 2 angiotensin receptor binding, Extracellular, Agt and IDBG-200169 and ENSMUSG00000031980 and 11606, AGT and IDBG-632058 and ENSBTAG00000012393 and 527114
1. Gene info
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