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anti-ADAM10 Antibody

  • Catalog number
    3201-100
  • Product name
    anti-ADAM10 Antibody
  • Size
    ADAM10 Antibody
  • Price
    338EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide corresponding to residue surrounding amino acid 735 of human ADAM10
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    ADAM10
  • Formulation of this antibody:
    100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-ADAM10 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 1% BSA, 0.02% thimerosal.
  • Alternative names of antibody target:
    MADM , CDw156, CD156c , kuz , EC 3.4.24.81, HsT18717
  • More antibodies
    v
  • Recommended usage:
    Western blotting (1-4 µg/ml) and immunofluorescence (2-10 µg/ml). An 85 kDa band corresponding to the precursor form of ADAM10 can be detected. Jurkat and K562 cell lysates can be used as positive controls. However, the optimal conditions should be determined individually.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-α, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-α, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
  • Concentration of antibody:
    0.5 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-ADAM10 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-ADAM metallopeptidase domain 10 (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    ADAM metallopeptidase domain 10, AD10 and AD18 and CD156c and HsT18717 and kuz and MADM and RAK, ADAM10 and IDBG-14155 and ENSG00000137845 and 102, this GO :0001701 and in utero embryonic development and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005798 and this GO lgi-associated vesicle and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006508 and proteolysis and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008219 and cell death and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0042117 and monocyte activation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0051088 and PMA-inducible membrane protein ectodomain proteolysis and biological process this GO :0051089 and constitutive protein ectodomain proteolysis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097038 and perinuclear endoplasmic reticulum and cellular component this GO :0097197 and tetraspanin-enriched microdomain and cellular component, protein homodimerization activity, this GO :0004175: endopeptidase activity and also this GO :0004222: metalloendopeptidase activity and also this GO :0005102: receptor binding and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0017124: SH3 domain binding and also this GO :0019901: protein kinase binding and also this GO :0042803: protein homodimerization activity, this GO :0004175: endopeptidase activity, this GO :0004222: metalloendopeptidase activity, this GO :0005102: receptor binding, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, this GO :0017124: SH3 domain binding, this GO :0019901: protein kinase binding, this GO :0042803: protein homodimerization activity, nuclei, Adam10 and IDBG-182594 and ENSMUSG00000054693 and 11487, ADAM10 and IDBG-646594 and ENSBTAG00000005481 and 282132
1. Gene info
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