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anti-ACHE Antibody (CT) (Clone 684CT8.3.4)

  • Catalog number
    6707-100
  • Product name
    anti-ACHE Antibody (CT) (Clone 684CT8.3.4)
  • Size
    ACHE Antibody (CT) (Clone 684CT8.3.4)
  • Price
    316EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Mouse
  • This antibody reacts with:
    Human, mouse, rat
  • Purification method:
    This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Immunogene sequence:
    This ACHE antibody is generated from mouse immunized with a KLH conjugated synthetic peptide between 587-611 amino acids from the C-terminal region of human ACHE.
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    ACHE
  • Formulation of this antibody:
    100 µl of antibody in PBS with 0.09% (W/V) sodium azide
  • Alternative names of antibody target:
    ACHE; Acetylcholinesterase
  • Recommended usage:
    Western blot: ~1:2000
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Monoclonal
  • Isotype:
    Mouse IgG1
  • Clone:
    684CT8.3.4
  • Background information:
    Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions. Alternative mRNA splicing gives rise to three forms of AChE. It plays a role in neuronal apoptosis. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers. The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer’s disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-ACHE Antibody (CT) (Clone 684CT8.3.4)
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-acetylcholinesterase (Antibody to) (CT) (clonality 684CT8.3.4)
  • Alternative technique
    antibodies
  • Alternative to gene target
    acetylcholinesterase, ACEE and ARACHE and N-ACHE and YT, ACHE and IDBG-32513 and ENSG00000087085 and 43, this GO :0001507 and acetylcholine catabolic process in synaptic cleft and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0001919 and regulation of receptor recycling and biological process this GO :0002076 and osteoblast development and biological process this GO :0003990 and acetylcholinesterase activity and molecular function this GO :0004104 and cholinesterase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005605 and basal lamina and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006260 and DNA replication and biological process this GO :0006581 and acetylcholine catabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006656 and phosphatidylcholine biosynthetic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007271 and synaptic transmission, cholinergic and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0007517 and muscle organ development and biological process this GO :0008152 and metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0009611 and response to wounding and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016787 and hydrolase activity and molecular function this GO :0017171 and serine hydrolase activity and molecular function this GO :0019695 and choline metabolic process and biological process this GO :0030054 and cell junction and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0031594 and neuromuscular junction and cellular component this GO :0031623 and receptor internalization and biological process this GO :0032223 and negative regulation of synaptic transmission, cholinergic and biological process this GO :0042136 and neurotransmitter biosynthetic process and biological process this GO :0042166 and acetylcholine binding and molecular function this GO :0042734 and presynaptic membrane and cellular component this GO :0042803 and protein homodimerization activity and molecular function this GO :0042982 and amyloid precursor protein metabolic process and biological process this GO :0043236 and laminin binding and molecular function this GO :0043621 and protein self-association and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045202 and synapse and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045212 and neurotransmitter receptor biosynthetic process and biological process this GO :0046474 and glycerophospholipid biosynthetic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0050714 and positive regulation of protein secretion and biological process this GO :0050770 and regulation of axonogenesis and biological process this GO :0051262 and protein tetramerization and biological process this GO :0060041 and retina development in camera-type eye and biological process, protein self-association, this GO :0001540: beta-amyloid binding and also this GO :0003990: acetylcholinesterase activity and also this GO :0004104: cholinesterase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0016787: hydrolase activity and also this GO :0017171: serine hydrolase activity and also this GO :0042166: acetylcholine binding and also this GO :0042803: protein homodimerization activity and also this GO :0043236: laminin binding and also this GO :0043621: protein self-association, this GO :0001540: beta-amyloid binding, this GO :0003990: acetylcholinesterase activity, this GO :0004104: cholinesterase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0016787: hydrolase activity, this GO :0017171: serine hydrolase activity, this GO :0042166: acetylcholine binding, this GO :0042803: protein homodimerization activity, this GO :0043236: laminin binding, this GO :0043621: protein self-association, nuclei, Ache and IDBG-204838 and ENSMUSG00000023328 and 11423, ACHE and IDBG-640435 and ENSBTAG00000001139 and 540446
  • Clone name
    684CT8.3.4
1. Gene info
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