GENTAUR Contact Gentaur

Up

GENTAUR Survey

GENTAUR EUROPE

+32 1658 9045
+32 1650 9045

BELGIUM

tel +32 2 732 5688
fax +32 2 732 4414
info@gentaur.com
Av. de l' Armée 68
B-1040 Brussels

France

tel 01 43 25 01 50
fax 01 43 25 01 60
9, rue Lagrange
75005 Paris

Italy

tel 02 36 00 65 93
fax 02 36 00 65 94
20135 Milano

Germany

tel +32 16 58 90 45
fax +32 16 50 90 45
Forckenbeckstraße 6
D-52074 Aachen

Japan

tel +81 78 386 0860
fax +81 78 306 0296
Minaatojimaminami-manchi
Chuo-ku, Kobe
065-0047


Catestatin

A New Hypertension / Stress / Insomnia / Cancer Biomarker

  • acts as a potent endogenous nicotinic cholinergic antagonist to inhibit catecholamine release.
  • induces release of histamine from mast cells.
  • displays potent antimicrobial activity

Relationship of CHGA-mediated dense-core secretory granule (DCG) biogenesis, catecholamine (CA) secretion, and its subsequent inhibition by the CHGA-derived peptide catestatin in the maintenance of blood pressure by the adrenal gland. CHGA, as a full-length molecule, initiates dense-core secretory granule biogenesis at the trans-Golgi network of adrenal chromaffin cells. Current data suggests that CHGA enhances granule biogenesis by preventing posttranslational degradation of other granule proteins in the Golgi complex. In the cytoplasm, catecholamine is synthesized and transported into the dense-core secretory granules via vesicular monoamine transporters. Upon stimulation by acetylcholine (Ach), catecholamine is coreleased with CHGA and catestatin from the granules. Secreted catecholamine triggers cardiovascular target cells to augment blood flow. This sympathoadrenal activity is then antagonized by the action of catestatin on cholinergic receptors to inhibit catecholamine secretion. [Ca2+]i, intracellular calcium concentration.

Taeyoon Kim and Y. Peng Loh. J. Clin. Invest. 115:1711-1713 (2005)

 

 

Cat #

Product

Quantity

Price

FC3-G-053-27

Catestatin (Human) - Cy3 Labeled Purified IgG

100 µl

709 €

FC3-053-27

Catestatin (Human) - Cy3 Labeled

1 nmol

394 €

RK-053-27

Catestatin (Human) RIA Kit

1 kit

616 €

G-053-27

Catestatin (Human) - Purified IgG Antibody

100 µg

394 €

FC5-G-053-27

Catestatin (Human) - Cy5 Labeled Purified IgG

100 µl

709 €

T-053-27

Catestatin (Human) - I-125 Labeled

10 µCi

765 €

EK-053-27

Catestatin (Human)

1 kit

462 €

H-053-27

Catestatin (Human) - Antibody for Western Blot

100 µl

394 €

FG-G-053-27A

Catestatin (Human) - FAM Labeled Purified IgG

100 µl

524 €

B-053-27

Catestatin (Human) - Biotin Labeled

10 µg

277 €

FEK-053-27

Catestatin (Human)

1 kit

585 €

FG-053-27B

Catestatin (Human) - FITC Labeled

1 nmol

277 €

FG-G-053-27B

Catestatin (Human) - FITC Labeled Purified IgG

100 µl

524 €

B-G-053-27

Catestatin (Human) - Biotin Labeled Purified IgG

100 µl

524 €

FC5-053-27

Catestatin (Human) - Cy5 Labeled

1 nmol

394 €

FG-053-27A

Catestatin (Human) - FAM Labeled

1 nmol

277 €

FR-G-053-27

Catestatin (Human) - Rhodamine Labeled Purified IgG

100 µl

641 €

053-27

Catestatin (Human)

200 µg

154 €

FG-053-28B

Catestatin (Mouse) - FITC Labeled

1 nmol

277 €

FC3-053-28

Catestatin (Mouse) - Cy3 Labeled

1 nmol

394 €

G-053-28

Catestatin (Mouse) - Purified IgG Antibody

100 µg

394 €

FG-G-053-28A

Catestatin (Mouse) - FAM Labeled Purified IgG

100 µl

462 €

H-053-28

Catestatin (Mouse) - Antiserum for Immunohistochemistry

100 ul

394 €

T-053-28

Catestatin (Mouse) - I-125 Labeled

10 µCi

765 €

FG-G-053-28B

Catestatin (Mouse) - FITC Labeled Purified IgG

100 µl

462 €

B-G-053-28

Catestatin (Mouse) - Biotin labeled purified IgG

100 µl

462 €

B-053-28

Catestatin (Mouse) - Biotin Labeled

10 µg

277 €

053-28

Catestatin (Mouse)

200 µg

154 €

FR-G-053-28

Catestatin (Mouse) - Rhodamine Labeled Purified IgG

100 µl

518 €

FC3-G-053-28

Catestatin (Mouse) - Cy3 Labeled Purified IgG

100 µl

585 €

FG-053-28A

Catestatin (Mouse) - FAM Labeled

1 nmol

277 €

FC5-053-28

Catestatin (Mouse) - Cy5 Labeled

1 nmol

394 €

RK-053-28

Catestatin (Mouse) RIA Kit

1 kit

616 €

FC5-G-053-28

Catestatin (Mouse) - Cy5 Labeled Purified IgG

100 µl

585 €

FG-053-29B

Catestatin (Rat) - FITC Labeled

1 nmol

277 €

FC3-053-29

Catestatin (Rat) - Cy3 Labeled

1 nmol

394 €

EK-053-29

Catestatin (Rat)

1 kit

462 €

FG-G-053-29A

Catestatin (Rat) - FAM Labeled Purified IgG

100 µl

462 €

H-053-29

Catestatin (Rat) - Antiserum for Immunohistochemistry

100 µl

394 €

T-053-29

Catestatin (Rat) - I-125 Labeled

10 µCi

765 €

FEK-053-29

Catestatin (Rat)

96 well - Fluorescent EIA Kit

585 €

FG-G-053-29B

Catestatin (Rat) - FAM Labeled Purified IgG

100 µl

462 €

B-G-053-29

Catestatin (Rat) - Biotin labeled purified IgG

100 µl

462 €

B-053-29

Catestatin (Rat) - Biotin Labeled

10 µg

277 €

053-29

Catestatin (Rat)

200 µg

154 €

FR-G-053-29

Catestatin (Rat) - Rhodamine Labeled Purified IgG

100 µl

518 €

FC3-G-053-29

Catestatin (Rat) - Cy3 Labeled Purified IgG

100 µl

585 €

FG-053-29A

Catestatin (Rat) - FAM Labeled

1 nmol

277 €

FC5-053-29

Catestatin (Rat) - Cy5 Labeled

1 nmol

394 €

G-053-29

Catestatin (Rat) - Purified IgG Antibody

100 µg

369 €

FC5-G-053-29

Catestatin (Rat) - Cy5 Labeled Purified IgG

100 µl

585 €

 

Home ] Up ]

Send mail to webmaster@gentaur.com with questions or comments about this web site.
Copyright © 2008 Gentaur Molecular Products
Site powered by Acid Dragon (AC)
Last modified: 07/15/09